ABSTRACT
The aim of this study was to evaluate the effect of underwear made of ethylene vinyl alcohol (EVOH) fiber in children with atopic dermatitis (AD). Twenty-one AD children (11 EVOH group and 10 control group) were studied for 4 weeks. Their AD severity based on the Scoring Atopic Dermatitis (SCORAD) score and physiological functions were assessed. The objective SCORAD significantly decreased in both groups. However, the SCORAD score (P<0.01) and urinary cortisol levels (P<0.05) were decreased only in EVOH group. It was concluded that EVOH fiber underwear might be useful for children with atopic dermatitis.
Subject(s)
Child , Child, Preschool , Clothing , Dermatitis, Atopic/epidemiology , Double-Blind Method , Ethanol , Ethylenes , Female , Humans , Male , TextilesSubject(s)
Adolescent , Adult , Child , Child, Preschool , Dermatitis, Atopic/complications , Disease Outbreaks , Female , Herpesvirus 1, Human/isolation & purification , Herpesvirus 2, Human/isolation & purification , Humans , Incidence , Infant , Japan/epidemiology , Kaposi Varicelliform Eruption/epidemiology , Male , Polymerase Chain ReactionSubject(s)
Administration, Cutaneous , Adult , Antibodies, Viral/blood , Eczema/drug therapy , Herpesvirus 1, Human/isolation & purification , Humans , Immunosuppressive Agents/adverse effects , Infant, Newborn , Kaposi Varicelliform Eruption/chemically induced , Male , Ointments , Tacrolimus/adverse effectsABSTRACT
INTRODUCTION: Patients with atopic dermatitis suffered from night-time wakening, but the exact mechanism of it was not known. Ghrelin was involved in growth hormone secretion, regulation of appetite, anxiety,night-time wakening and stress. METHODS: Thus salivary ghreli levels during the night were measured in 40 healthy children or 40 patients with atopic dermatitis with night-time wakening. Salivary ghrelin levels at 02:00 h were markedly elevated in patients with atopic dermatitis compared to those in healthy children. RESULTS: Neither viewing control non-humorous film nor viewing humorous film had any effect on healthy children. In contrast, viewing humorous film improved night-time wakening and reduced elevation of salivary ghrelin levels in patients with atopic dermatitis, while viewing control film failed to do so. CONCLUSION: Viewing humorous film may be useful in the treatment of night-time wakening in patients with atopic dermatitis.
Subject(s)
Case-Control Studies , Child , Child, Preschool , Dermatitis, Atopic/metabolism , Emotions , Female , Ghrelin , Humans , Laughter/psychology , Laughter Therapy , Male , Peptide Hormones/metabolism , Saliva , Sleep Initiation and Maintenance Disorders/metabolism , Stress, Psychological/complications , WakefulnessABSTRACT
Fatty liver in non-obese Japanese children was observed in 3.2% of non-atopic children and in 17.6% of patients with atopic dermatitis in 2000. The prevalence of fatty liver in non-obese children aged 0-12 years was studied from 2001 to 2003. Subjects were either non-atopic children, or suffering from bronchial asthma, allergic rhinitis, or atopic dermatitis. Fatty liver was studied by abdominal ultrasound scans. The prevalence of fatty liver was increasing annually, and it reached to 12.5% in non-atopic children, 13.1% in patients with bronchial asthma, 13.7% in patients with allergic rhinitis, or 33.9% in patients with atopic dermatitis, in 2003. Since fatty liver in childhood may be a risk factor for lifestyle-related diseases in future, care should be taken to prevent it.